Egr2^tm1Pwg
Targeted Allele Detail

Summary

• Symbol: Egr2^tm1Pwg
• Name: early growth response 2; targeted mutation 1, Ping Wang
• MGI ID: MGI:6715310
• Synonyms: GFP-Egr2
• Gene: Egr2 Location: Chr10:67371305-67378018 bp, + strand Genetic Position: Chr10, 34.96 cM, cytoband B5
• Alliance: Egr2^tm1Pwg page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:243871
• Parent Cell Line: JM8 (ES Cell)
• Strain of Origin: C57BL/6N

Mutation description

• Allele Type: Targeted (Reporter)
• Mutation: Insertion
• Mutation details: The targeting construct inserted an EGFP reporter gene at the translation initiation site. A neomycin resistance cassette was inserted into the untranslated region of exon 2. (J:243871)

Expression

In Mice Carrying this Mutation:

2 RNA-Seq or microarray experiment(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 3 strains available Cell Lines: 0 lines available
• Carrying any Egr2 Mutation: 32 strains or lines available

References

• Original: J:243871 Miao T, et al., Egr2 and 3 control adaptive immune responses by temporally uncoupling expansion from T cell differentiation. J Exp Med. 2017 Jun 05;214(6):1787-1808
• All: 3 reference(s)