Odaph^em1Jcch
Endonuclease-mediated Allele Detail

Summary

• Symbol: Odaph^em1Jcch
• Name: odontogenesis associated phosphoprotein; endonuclease-mediated mutation 1, Jan Hu
• MGI ID: MGI:6715274
• Synonyms: Odaph^C41X
• Gene: Odaph Location: Chr5:92135332-92143176 bp, + strand Genetic Position: Chr5, 45.68 cM
• Alliance: Odaph^em1Jcch page

Mutation origin

• Strain of Origin: C57BL/6N

Mutation description

• Allele Type: Endonuclease-mediated (Not Specified)
• Mutation: Single point mutation
• Mutation details: CRISPR-targeting generated a stop codon at 41 cysteine (TGC) to Stop (TGA), which was predicted to result in loss of function. This codon change corresponded to the ODAPH (c.129C>A [p.Cys43*]) mutation identified in an Iraqi family with amelogenesis imperfecta, AI2A4 (J:94077)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Odaph Mutation: 6 strains or lines available

References

• Original: J:94077 Mutant Mouse Regional Resource Centers, Information obtained from the Mutant Mouse Regional Resource Centers (MMRRC). Unpublished. 2004-2015
• All: 1 reference(s)