Tg(Neurog2-cre/ERT2)G2ATahi
Transgene Detail

Summary

• Symbol: Tg(Neurog2-cre/ERT2)G2ATahi
• Name: transgene insertion G2A, Tatsumi Hirata
• MGI ID: MGI:6712679
• Synonyms: Neurog2^CreER(G2A)
• Transgene: Tg(Neurog2-cre/ERT2)G2ATahi Location: unknown
• Alliance: Tg(Neurog2-cre/ERT2)G2ATahi page

Transgene origin

• Strain of Origin: C57BL/6

Transgene description

• Transgene Type: Transgenic (Inducible, Recombinase)
• Inducer: tamoxifen
• Mutation: Insertion
• Tg(Neurog2-cre/ERT2)G2ATahi expression driven by 1 gene
  Transgene expression driven by:
  

  Organism	Driver Gene	Note
  mouse	Neurog2 (MGI:109619)

• Mutation details: The transgene was constructed using a genomic BAC clone RP23-360O22 encoding the mouse neurogenin (Neurog)2 gene by replacing the entire coding sequence in exon2 with a CreERT2 cassette. The three mouse lines that independently received the transgene integration were then assayed for the Cre recombinase activities. Through this screen, one line (G2A) was selected by the highest recombination rate in OB neurons. (J:288786)

Recombinase activity

Activity:	Tissue activity of this recombinase allele
Driver:	Neurog2 (mouse) Summary of all recombinase alleles driven by Neurog2. Comparative matrix view of recombinase activities Alliance mouse Neurog2 gene page

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:288786 Hirata T, et al., A Novel Birthdate-Labeling Method Reveals Segregated Parallel Projections of Mitral and External Tufted Cells in the Main Olfactory System. eNeuro. 2019 Nov/Dec;6(6):ENEURO.0234-19.2019
• All: 4 reference(s)