Bckdk^em1Eze
Endonuclease-mediated Allele Detail

Summary

• Symbol: Bckdk^em1Eze
• Name: branched chain ketoacid dehydrogenase kinase; endonuclease-mediated mutation 1, Elazar Zelzer
• MGI ID: MGI:6711989
• Gene: Bckdk Location: Chr7:127503245-127508836 bp, + strand Genetic Position: Chr7, 69.82 cM
• Alliance: Bckdk^em1Eze page

Mutation origin

• Strain of Origin: Not Applicable

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• CRISPR-targeting deleted 884 bp. (J:303714)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Bckdk Mutation: 46 strains or lines available

References

• Original: J:303714 Heinemann-Yerushalmi L, et al., BCKDK regulates the TCA cycle through PDC in the absence of PDK family during embryonic development. Dev Cell. 2021 Mar 23
• All: 1 reference(s)