Il2^tm1.2Kasm
Targeted Allele Detail

Summary

• Symbol: Il2^tm1.2Kasm
• Name: interleukin 2; targeted mutation 1.2, Kendall A Smith
• MGI ID: MGI:6711506
• Gene: Il2 Location: Chr3:37174862-37180103 bp, - strand Genetic Position: Chr3, 18.3 cM, cytoband B-C
• Alliance: Il2^tm1.2Kasm page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:305560
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: C57BL/6

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Il2 Mutation: 32 strains or lines available

References

• Original: J:305560 Dikiy S, et al., A distal Foxp3 enhancer enables interleukin-2 dependent thymic Treg cell lineage commitment for robust immune tolerance. Immunity. 2021 May 11;54(5):931-946.e11
• All: 1 reference(s)