Caskin1^tm1.1Lasb
Targeted Allele Detail

Summary

• Symbol: Caskin1^tm1.1Lasb
• Name: CASK interacting protein 1; targeted mutation 1.1, Laszlo Buday
• MGI ID: MGI:6711391
• Synonyms: Caskin1^-
• Gene: Caskin1 Location: Chr17:24707575-24727645 bp, + strand Genetic Position: Chr17, 12.4 cM, cytoband A3.3
• Alliance: Caskin1^tm1.1Lasb page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:297862
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: C57BL/6N

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: A loxP site and an FRT site flanked neomycin resistance gene cassette were inserted into intron 1 and a second loxP site into intron 6. Exons 2-6 and the neo cassette were deleted through subsequent cre-mediated recombination. (J:297862)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Caskin1 Mutation: 61 strains or lines available

References

• Original: J:297862 Bencsik N, et al., Dendritic spine morphology and memory formation depend on postsynaptic Caskin proteins. Sci Rep. 2019 Nov 14;9(1):16843
• All: 1 reference(s)