Peg13^tm1Ploen
Targeted Allele Detail

Summary

• Symbol: Peg13^tm1Ploen
• Name: paternally expressed 13; targeted mutation 1, Diethard Tautz
• MGI ID: MGI:6711261
• Synonyms: Peg13^tm1Mevb
• Gene: Peg13 Location: Chr15:72677451-72682173 bp, - strand Genetic Position: Chr15, 33.86 cM
• Alliance: Peg13^tm1Ploen page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:304782
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Conditional ready)
• Mutations: Insertion, Intragenic deletion
• Mutation details: An FRT-flanked neomycin selection cassette replaced the 3' part of the transcript and loxP sites flanking the whole gene were inserted to allow a full deletion on top of the partial deletion. Flp-mediated recombination removed the selection cassette. Only the 3 part of the RNA is removed, without affecting the CpG island. (J:304782)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Peg13 Mutation: 0 strains or lines available

References

• Original: J:304782 Keshavarz M, et al., The imprinted lncRNA Peg13 regulates sexual preference and the sex-specific brain transcriptome in mice. Proc Natl Acad Sci U S A. 2021 Mar 9;118(10):e2022172118
• All: 1 reference(s)