Cd40lg^em1(srta)Vic
Endonuclease-mediated Allele Detail

Summary

• Symbol: Cd40lg^em1(srta)Vic
• Name: CD40 ligand; endonuclease-mediated mutation 1, Gabriel Victora
• MGI ID: MGI:6695967
• Synonyms: Cd40lg^SrtA, Cd40lg^SrtA1
• Gene: Cd40lg Location: ChrX:56257503-56269402 bp, + strand Genetic Position: ChrX, 31.21 cM
• Alliance: Cd40lg^em1(srta)Vic page

Mutation origin

• Strain of Origin: C57BL/6

Mutation description

• Allele Type: Endonuclease-mediated (Epitope tag)
• Mutation: Insertion
• Mutation details: CRISPR-targeting replaced the STOP codon in exon 5 with a floxed stop cassette and the Staphylococcus aureus transpeptidase sortase A (srta) coding sequence. (J:304776)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Cd40lg Mutation: 14 strains or lines available

References

• Original: J:304776 Pasqual G, et al., Monitoring T cell-dendritic cell interactions in vivo by intercellular enzymatic labelling. Nature. 2018 Jan 25;553(7689):496-500
• All: 3 reference(s)