Shisa7^em1Wlu
Endonuclease-mediated Allele Detail

Summary

• Symbol: Shisa7^em1Wlu
• Name: shisa family member 7; endonuclease-mediated mutation 1, Wei Lu
• MGI ID: MGI:6694854
• Gene: Shisa7 Location: Chr7:4828551-4847695 bp, - strand Genetic Position: Chr7, 2.79 cM
• Alliance: Shisa7^em1Wlu page

Mutation origin

• Strain of Origin: C57BL/6NCrl

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• Mutation details: CRISPR/Cas9 genome editing technology was used to generate a deletion spanning from exon 2 to exon 7. (J:281687)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Shisa7 Mutation: 15 strains or lines available

References

• Original: J:281687 Han W, et al., Shisa7 is a GABAA receptor auxiliary subunit controlling benzodiazepine actions. Science. 2019 Oct 11;366(6462):246-250
• All: 2 reference(s)