Rimklb^em1Matak
Endonuclease-mediated Allele Detail

Summary

• Symbol: Rimklb^em1Matak
• Name: ribosomal modification protein rimK-like family member B; endonuclease-mediated mutation 1, Masaoki Takano
• MGI ID: MGI:6693818
• Synonyms: Rimklb^A29del,L30V
• Gene: Rimklb Location: Chr6:122424255-122464021 bp, - strand Genetic Position: Chr6, 57.55 cM, cytoband F2
• Alliance: Rimklb^em1Matak page

Mutation origin

• Strain of Origin: C57BL/6J

Mutation description

• Allele Type: Endonuclease-mediated (Not Specified)
• Mutation: Intragenic deletion
• Mutation details: CRISPR/Cas9 technology generated a 3 bp deletion (CGT) resulting in the deletion of alanine at amino acid 29 and a leucine to valine substitution at amino acid 30. (J:303850)

Expression

In Structures Affected by this Mutation:

4 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Rimklb Mutation: 63 strains or lines available

References

• Original: J:303850 Maekura K, et al., Rimklb mutation causes male infertility in mice. Sci Rep. 2021 Feb 25;11(1):4604
• All: 1 reference(s)