Lcp2^em1Cya
Endonuclease-mediated Allele Detail

Summary

• Symbol: Lcp2^em1Cya
• Name: lymphocyte cytosolic protein 2; endonuclease-mediated mutation 1, Cyagen Biosciences
• MGI ID: MGI:6693449
• Synonyms: Lcp2^em1Cgen, Lcp2^em1cyagen, SLP76^-
• Gene: Lcp2 Location: Chr11:33996928-34042281 bp, + strand Genetic Position: Chr11, 19.43 cM
• Alliance: Lcp2^em1Cya page

Mutation origin

• Strain of Origin: C57BL/6J

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• Exons 2-3 were targeted. (J:300870)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Lcp2 Mutation: 42 strains or lines available

References

• Original: J:300870 Yan Z, et al., Targeting adaptor protein SLP76 of RAGE as a therapeutic approach for lethal sepsis. Nat Commun. 2021 Jan 12;12(1):308
• All: 1 reference(s)