Ufsp2^em1Hwv
Endonuclease-mediated Allele Detail

Summary

• Symbol: Ufsp2^em1Hwv
• Name: UFM1-specific peptidase 2; endonuclease-mediated mutation 1, Herbert W Virgin
• MGI ID: MGI:6693433
• Synonyms: Ufsp2^f
• Gene: Ufsp2 Location: Chr8:46428565-46449995 bp, + strand Genetic Position: Chr8, 25.96 cM
• Alliance: Ufsp2^em1Hwv page

Mutation origin

• Strain of Origin: C57BL/6J

Mutation description

• Allele Type: Endonuclease-mediated (Conditional ready)
• Mutation: Insertion
• Exon 5 was flanked by loxP sites. (J:300137)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Ufsp2 Mutation: 24 strains or lines available

References

• Original: J:300137 Balce DR, et al., UFMylation inhibits the proinflammatory capacity of interferon-gamma-activated macrophages. Proc Natl Acad Sci U S A. 2021 Jan 5;118(1):e2011763118
• All: 1 reference(s)