Asb1^em1Gpt
Endonuclease-mediated Allele Detail

Summary

• Symbol: Asb1^em1Gpt
• Name: ankyrin repeat and SOCS box-containing 1; endonuclease-mediated mutation 1, GemPharmatech Co., Ltd
• MGI ID: MGI:6693428
• Gene: Asb1 Location: Chr1:91468266-91487311 bp, + strand Genetic Position: Chr1, 46.19 cM
• Alliance: Asb1^em1Gpt page

Mutation origin

• Strain of Origin: C57BL/6J

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Not Specified
• CRIPSR/Cas9 genome editing technology was used to generate a deletion of all exons of the gene. (J:300756)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Asb1 Mutation: 26 strains or lines available

References

• Original: J:300756 Hou P, et al., An unconventional role of an ASB family protein in NF-kappaB activation and inflammatory response during microbial infection and colitis. Proc Natl Acad Sci U S A. 2021 Jan 19;118(3):e2015416118
• All: 1 reference(s)