Aff4^tm1.1Jlb
Targeted Allele Detail

Summary

• Symbol: Aff4^tm1.1Jlb
• Name: AF4/FMR2 family, member 4; targeted mutation 1.1, Janice L Brissette
• MGI ID: MGI:6693284
• Gene: Aff4 Location: Chr11:53241660-53312657 bp, + strand Genetic Position: Chr11, 31.93 cM
• Alliance: Aff4^tm1.1Jlb page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:301543
• Parent Cell Line: KV1 (ES Cell)
• Strain of Origin: (C57BL/6J x 129S6/SvEvTac)F1

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• Mutation details: Exons 10 and 11 were floxed. Flp-mediated recombination removed the FRT-flanked neomycin resistance cassette inserted downstream of exon 11. (J:301543)

Expression

In Mice Carrying this Mutation:

3 assay results 1 RNA-Seq or microarray experiment(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Aff4 Mutation: 92 strains or lines available

References

• Original: J:301543 Li J, et al., Modeling by disruption and a selected-for partner for the nude locus. EMBO Rep. 2020 Dec 28;:e49804
• All: 1 reference(s)