Mc3rtm1.1(cre)Dolsn
Targeted Allele Detail
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Symbol: |
Mc3rtm1.1(cre)Dolsn |
Name: |
melanocortin 3 receptor; targeted mutation 1.1, David P Olson |
MGI ID: |
MGI:6690499 |
Synonyms: |
Mc3rcre |
Gene: |
Mc3r Location: Chr2:172090412-172093034 bp, + strand Genetic Position: Chr2, 94.8 cM
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Alliance: |
Mc3rtm1.1(cre)Dolsn page
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Germline Transmission: |
Earliest citation of germline transmission:
J:270010
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Parent Cell Line: |
Not Specified (ES Cell)
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Strain of Origin: |
Not Specified
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Allele Type: |
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Targeted (Recombinase) |
Mutation: |
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Insertion
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Mc3rtm1.1(cre)Dolsn expression driven by
1 gene
Knock-in expression driven by:
Organism |
Driver Gene |
Note |
mouse |
Mc3r (MGI:96929) |
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Mutation details: The targeting construct containing a T2A-Cre fusion cassette replaced the stop codon of the mouse Mc3r gene. The neo selection marker was excised by breeding chimeric mice to Flp deleter animals.
(J:270010)
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Activity: |
Tissue activity of this recombinase allele
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Driver:
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Mc3r
(mouse)
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Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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Carrying any Mc3r Mutation: |
31 strains or lines available
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Original: |
J:270010 Pei H, et al., Lateral Hypothalamic Mc3R-Expressing Neurons Modulate Locomotor Activity, Energy Expenditure, and Adiposity in Male Mice. Endocrinology. 2019 Feb 1;160(2):343-358 |
All: |
2 reference(s) |
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