Phf7^em1Osb
Endonuclease-mediated Allele Detail

Summary

• Symbol: Phf7^em1Osb
• Name: PHD finger protein 7; endonuclease-mediated mutation 1, Research Institute for Microbial Diseases, Osaka University
• MGI ID: MGI:6690453
• Synonyms: Phf7^-4
• Gene: Phf7 Location: Chr14:30959646-30973274 bp, - strand Genetic Position: Chr14, 19.09 cM
• Alliance: Phf7^em1Osb page

Mutation origin

• Strain of Origin: (C57BL/6NJcl x DBA/2NJcl)F2

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• CRISPR-targeting removed 4 bp to generate a null allele. (J:298823)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 2 strains available Cell Lines: 0 lines available
• Carrying any Phf7 Mutation: 24 strains or lines available

References

• Original: J:298823 Kim CR, et al., PHF7 Modulates BRDT Stability and Histone-to-Protamine Exchange during Spermiogenesis. Cell Rep. 2020 Jul 28;32(4):107950
• All: 1 reference(s)