Aplnrem3(cre/ERT2)Smoc
Endonuclease-mediated Allele Detail
|
Symbol: |
Aplnrem3(cre/ERT2)Smoc |
Name: |
apelin receptor; endonuclease-mediated mutation 3, Shanghai Model Organisms Center |
MGI ID: |
MGI:6690419 |
Synonyms: |
Apj-CreER |
Gene: |
Aplnr Location: Chr2:84966704-84970267 bp, + strand Genetic Position: Chr2, 49.45 cM, cytoband E1
|
Alliance: |
Aplnrem3(cre/ERT2)Smoc page
|
|
|
Allele Type: |
|
Endonuclease-mediated (Inducible, Recombinase) |
Inducer: |
|
tamoxifen |
Mutation: |
|
Insertion
|
|
|
Aplnrem3(cre/ERT2)Smoc expression driven by
1 gene
Knock-in expression driven by:
|
|
|
Mutation details: Using the CRISPR/Cas9 technology cre/ERT2 cassette was targeted to the translational start codon ATG of the mouse Aplnr gene via homologous recombination.
(J:270635)
|
|
|
Activity: |
Tissue activity of this recombinase allele
|
Driver:
|
Aplnr
(mouse)
|
|
|
|
Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
|
Carrying any Aplnr Mutation: |
28 strains or lines available
|
|
Original: |
J:270635 Zhao H, et al., Apj(+) Vessels Drive Tumor Growth and Represent a Tractable Therapeutic Target. Cell Rep. 2018 Oct 30;25(5):1241-1254.e5 |
All: |
3 reference(s) |
|