Tob2^tm1Nju
Targeted Allele Detail

Summary

• Symbol: Tob2^tm1Nju
• Name: transducer of ERBB2, 2; targeted mutation 1, Model Animal Research Center of Nanjing University
• MGI ID: MGI:6682151
• Synonyms: Tob2^flox
• Gene: Tob2 Location: Chr15:81732473-81742997 bp, - strand Genetic Position: Chr15, 38.26 cM, cytoband E2
• Alliance: Tob2^tm1Nju page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:300677
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• A conditional allele was generated. (J:300677)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Tob2 Mutation: 22 strains or lines available

References

• Original: J:300677 Jiang G, et al., Tob2 Inhibits TLR-Induced Inflammatory Responses by Association with TRAF6 and MyD88. J Immunol. 2020 Aug 15;205(4):981-986
• All: 1 reference(s)