Acox1^em1Wum
Endonuclease-mediated Allele Detail

Summary

• Symbol: Acox1^em1Wum
• Name: acyl-Coenzyme A oxidase 1, palmitoyl; endonuclease-mediated mutation 1, Washington University School of Medicine
• MGI ID: MGI:6682059
• Synonyms: Acox1^Lox
• Gene: Acox1 Location: Chr11:116062714-116089605 bp, - strand Genetic Position: Chr11, 80.96 cM
• Alliance: Acox1^em1Wum page

Mutation origin

• Strain of Origin: Not Applicable

Mutation description

• Allele Type: Endonuclease-mediated (Conditional ready, No functional change)
• Mutation: Insertion
• CRISPR-targeting floxed exon 7. (J:270463)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Acox1 Mutation: 42 strains or lines available

References

• Original: J:270463 Park H, et al., Peroxisome-derived lipids regulate adipose thermogenesis by mediating cold-induced mitochondrial fission. J Clin Invest. 2019 Feb 1;129(2):694-711
• All: 2 reference(s)