Rr550tm1.1Knd
Targeted Allele Detail
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Symbol: |
Rr550tm1.1Knd |
Name: |
regulatory region 550; targeted mutation 1.1, Hisato Kondoh |
MGI ID: |
MGI:6682027 |
Synonyms: |
Sox2N2-, Sox2tm2.1Knd |
Gene: |
Rr550 Location: Chr3:34700326-34700717 bp Genetic Position: Chr3, Syntenic
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Alliance: |
Rr550tm1.1Knd page
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Allele Type: |
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Targeted (Modified regulatory region) |
Mutations: |
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Insertion, Intragenic deletion
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Mutation details: A loxP and neomycin resistance gene cassette were placed upstream of the 538 bp sequence corresponding to the N2 (neural plate 2) enhancer located 3861 bp upstream of the gene and a second loxP site downstream. Cre-mediated recombination removed the selection cassette and enhancer.
(J:278249)
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Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
Carrying this Mutation: |
Mouse Strains: 1 strain available
Cell Lines: 0 lines available
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Carrying any Rr550 Mutation: |
0 strains or lines available
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Original: |
J:278249 Iwafuchi-Doi M, et al., The Pou5f1/Pou3f-dependent but SoxB-independent regulation of conserved enhancer N2 initiates Sox2 expression during epiblast to neural plate stages in vertebrates. Dev Biol. 2011 Apr 15;352(2):354-66 |
All: |
1 reference(s) |
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