Uxt^em1Chwa
Endonuclease-mediated Allele Detail

Summary

• Symbol: Uxt^em1Chwa
• Name: ubiquitously expressed prefoldin like chaperone; endonuclease-mediated mutation 1, Chen Wang
• MGI ID: MGI:6515773
• Synonyms: Uxt^flox
• Gene: Uxt Location: ChrX:20818162-20828259 bp, - strand Genetic Position: ChrX, 16.46 cM, cytoband A2
• Alliance: Uxt^em1Chwa page

Mutation origin

• Strain of Origin: C57BL/6

Mutation description

• Allele Type: Endonuclease-mediated (Conditional ready)
• Mutation: Insertion
• CRISPR/Cas9 technology was used to flank exon 3 with loxP sites. (J:303303)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Uxt Mutation: 5 strains or lines available

References

• Original: J:303303 Pan M, et al., Mice deficient in UXT exhibit retinitis pigmentosa-like features via aberrant autophagy activation. Autophagy. 2020 Aug 2;:1-16
• All: 1 reference(s)