Trim7^em1Raj
Endonuclease-mediated Allele Detail

Summary

• Symbol: Trim7^em1Raj
• Name: tripartite motif-containing 7; endonuclease-mediated mutation 1, Ricardo Rajsbaum
• MGI ID: MGI:6514752
• Synonyms: 0431B
• Gene: Trim7 Location: Chr11:48716965-48742019 bp, + strand Genetic Position: Chr11, 28.8 cM
• Alliance: Trim7^em1Raj page

Mutation origin

• Strain of Origin: C57BL/6N

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• Mutation details: CRISPR/cas9 mediated recombination created a 12,373 nt deletion (48837535-48849907 GRCm38) spanning from exon 1 to exon 7. (J:296988)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Trim7 Mutation: 42 strains or lines available

References

• Original: J:296988 Giraldo MI, et al., Envelope protein ubiquitination drives entry and pathogenesis of Zika virus. Nature. 2020 Sep;585(7825):414-419
• All: 1 reference(s)