Htr4^tm1.1Htz
Targeted Allele Detail

Summary

• Symbol: Htr4^tm1.1Htz
• Name: 5 hydroxytryptamine (serotonin) receptor 4; targeted mutation 1.1, Nathaniel Heintz
• MGI ID: MGI:6514016
• Synonyms: Htr4-Floxed, ROXY1G12
• Gene: Htr4 Location: Chr18:62457275-62629648 bp, + strand Genetic Position: Chr18, 35.1 cM, cytoband D3
• Alliance: Htr4^tm1.1Htz page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:303284
• Parent Cell Line: PRX-B6-albino #1 (ES Cell)
• Strain of Origin: B6(Cg)-Tyr^c-2J/J

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• Exon 5 was floxed. Flp-mediated recombination removed the selection cassette. (J:303284)

Expression

In Mice Carrying this Mutation:

1 RNA-Seq or microarray experiment(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Htr4 Mutation: 29 strains or lines available

References

• Original: J:303284 Karayol R, et al., Serotonin receptor 4 in the hippocampus modulates mood and anxiety. Mol Psychiatry. Jan 13
• All: 1 reference(s)