Del(13Zfp997-Vmn2r-ps103)1Aiwsk
Endonuclease-mediated Allele Detail

Summary

• Symbol: Del(13Zfp997-Vmn2r-ps103)1Aiwsk
• Name: deletion, Chr 13, Akiko Iwasaki 1
• MGI ID: MGI:6513143
• Synonyms: Gm10324^-
• Gene: Del(13Zfp997-Vmn2r-ps103)1Aiwsk Location: unknown Genetic Position: Chr13, Syntenic

Mutation origin

• Strain of Origin: Not Applicable

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutations: Intergenic deletion, Intragenic deletion
• Del(13Zfp997-Vmn2r-ps103)1Aiwsk involves 6 genes/genome features (Zfp997, Gm17514, Gm45965 ...) View all
• Mutation details: Several gRNAs were used to target this repetitive region using CRISPR/Cas9 technology, resulting in around 6 different genomic deletions. This allele represents a deletion encompassing the region from the 3' end of the KRAB type zinc finger protein 997 gene to (and including) the Vmn2r-ps103 pseudogene. (J:282526)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Del(13Zfp997-Vmn2r-ps103)1Aiwsk Mutation: 0 strains or lines available

References

• Original: J:282526 Treger RS, et al., The Lupus Susceptibility Locus Sgp3 Encodes the Suppressor of Endogenous Retrovirus Expression SNERV. Immunity. 2019 Feb 19;50(2):334-347.e9
• All: 1 reference(s)