Izumo1r^em1Nino
Endonuclease-mediated Allele Detail

Summary

• Symbol: Izumo1r^em1Nino
• Name: IZUMO1 receptor, JUNO; endonuclease-mediated mutation 1, Naokazu Inoue
• MGI ID: MGI:6511751
• Synonyms: Juno-KO
• Gene: Izumo1r Location: Chr9:14797110-14815245 bp, - strand Genetic Position: Chr9, 4.42 cM
• Alliance: Izumo1r^em1Nino page

Mutation origin

• Strain of Origin: Not Applicable

Mutation description

• Allele Type: Endonuclease-mediated (Modified isoform(s), Null/knockout)
• Mutation: Intragenic deletion
• Mutation details: CRISPR/Cas9 genome editing technology was used to generate a 31 bp deletion at the the initial methionine codon. (J:297089)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Izumo1r Mutation: 23 strains or lines available

References

• Original: J:297089 Inoue N, et al., Unveiling a novel function of CD9 in surface compartmentalization of oocytes. Development. 2020 Aug 14;147(15):dev189985
• All: 1 reference(s)