Apold1^tm1Pfw
Targeted Allele Detail

Summary

• Symbol: Apold1^tm1Pfw
• Name: apolipoprotein L domain containing 1; targeted mutation 1, Paul Worley
• MGI ID: MGI:6511000
• Synonyms: Verge KO
• Gene: Apold1 Location: Chr6:134958964-134963799 bp, + strand Genetic Position: Chr6, 65.77 cM
• Alliance: Apold1^tm1Pfw page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:302897
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Null/knockout, Reporter)
• Mutations: Insertion, Intragenic deletion
• Mutation details: The open reading frame was replaced with a beta-gal/neo cassette. Western blot analysis confirmed the absence of protein expression in the brain of homozygous mutant mice. (J:302852, J:302897)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Apold1 Mutation: 22 strains or lines available

References

• Original: J:302897 Liu F, et al., Loss of vascular early response gene reduces edema formation after experimental stroke. Exp Transl Stroke Med. 2012 Jun 8;4(1):12
• All: 4 reference(s)