Gpr82^tm1Shbg
Targeted Allele Detail

Summary

• Symbol: Gpr82^tm1Shbg
• Name: G protein-coupled receptor 82; targeted mutation 1, Torsten Schoneberg
• MGI ID: MGI:6510825
• Gene: Gpr82 Location: ChrX:13527602-13533672 bp, + strand Genetic Position: ChrX, 8.59 cM
• Alliance: Gpr82^tm1Shbg page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:301613
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Null/knockout, Reporter)
• Mutations: Insertion, Intragenic deletion
• Mutation details: A part of exon 4 (insertion between codon 1 and 254) containing the coding sequence was replaced by a cassette containing an EMCV-IRES site, lacZ gene and the neomycin resistance gene via homologous recombination. The Gpr82 gene lies within an intron of the Cask gene, however mRNA levels of Cask transcripts are unchanged, indicating that Cask is not affected. (J:301613)

Expression

In Structures Affected by this Mutation:

3 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Gpr82 Mutation: 10 strains or lines available

References

• Original: J:301613 Engel KM, et al., Reduced food intake and body weight in mice deficient for the G protein-coupled receptor GPR82. PLoS One. 2011;6(12):e29400
• All: 1 reference(s)