Slc2a10^tm1Tac
Targeted Allele Detail

Summary

• Symbol: Slc2a10^tm1Tac
• Name: solute carrier family 2 (facilitated glucose transporter), member 10; targeted mutation 1, Taconic
• MGI ID: MGI:6510237
• Gene: Slc2a10 Location: Chr2:165345817-165361837 bp, + strand Genetic Position: Chr2, 85.66 cM
• Alliance: Slc2a10^tm1Tac page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:295974
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutation: Insertion
• A LacZ/Neo selection cassette replaced exon 2 to through the beginning of exon 5. (J:295974)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Slc2a10 Mutation: 29 strains or lines available

References

• Original: J:295974 Boel A, et al., Slc2a10 knock-out mice deficient in ascorbic acid synthesis recapitulate aspects of arterial tortuosity syndrome and display mitochondrial respiration defects. Hum Mol Genet. 2020 Jun 3;29(9):1476-1488
• All: 1 reference(s)