Klf10^tm2Sub
Targeted Allele Detail

Summary

• Symbol: Klf10^tm2Sub
• Name: Kruppel-like transcription factor 10; targeted mutation 2, Malayannan Subramaniam
• MGI ID: MGI:6510232
• Synonyms: KLF10^flox, Klf10^L, Klf10^LoxP
• Gene: Klf10 Location: Chr15:38291707-38300950 bp, - strand Genetic Position: Chr15, 15.15 cM
• Alliance: Klf10^tm2Sub page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:247824
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Conditional ready)
• Mutation: Insertion
• Loxp sites were inserted into the introns surrounding exons 1 and 2. (J:247824)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Klf10 Mutation: 25 strains or lines available

References

• Original: J:247824 Weng CC, et al., KLF10 loss in the pancreas provokes activation of SDF-1 and induces distant metastases of pancreatic ductal adenocarcinoma in the KrasG12D p53flox/flox model. Oncogene. 2017 Sep 28;36(39):5532-5543
• All: 4 reference(s)