Bex1^em1Mori
Endonuclease-mediated Allele Detail

Summary

• Symbol: Bex1^em1Mori
• Name: brain expressed X-linked 1; endonuclease-mediated mutation 1, Masataka Mori
• MGI ID: MGI:6509427
• Gene: Bex1 Location: ChrX:135114721-135116262 bp, - strand Genetic Position: ChrX, 57.4 cM
• Alliance: Bex1^em1Mori page

Mutation origin

• Strain of Origin: C57BL/6J

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• Mutation details: A 7 bp deletion was created using the CRISPR/Cas9 system and 5-GTCGCAGGCGGTTCCGGGTTCGG-3. This deletion proximal downstream of the start codon causes a reading frameshift. (J:326964)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Bex1 Mutation: 4 strains or lines available

References

• Original: J:326964 Hibino E, et al., Bex1 is essential for ciliogenesis and harbours biomolecular condensate-forming capacity. BMC Biol. 2022 Feb 10;20(1):42
• All: 1 reference(s)