Fzd7^tm1.1Cle
Targeted Allele Detail

Summary

• Symbol: Fzd7^tm1.1Cle
• Name: frizzled class receptor 7; targeted mutation 1.1, Hans Clevers
• MGI ID: MGI:6508091
• Synonyms: Fzd7^fl
• Gene: Fzd7 Location: Chr1:59521583-59526114 bp, + strand Genetic Position: Chr1, 30.08 cM
• Alliance: Fzd7^tm1.1Cle page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:263295
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Conditional ready)
• Mutation: Insertion
• Mutation details: LoxP sites flank the single exon of the gene. An frt-flanked neomycin selection cassette was removed via FLP1-mediated recombination in the germline. (J:263295)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Fzd7 Mutation: 38 strains or lines available

References

• Original: J:263295 Flanagan DJ, et al., Frizzled7 functions as a Wnt receptor in intestinal epithelial Lgr5(+) stem cells. Stem Cell Reports. 2015 May 12;4(5):759-67
• All: 2 reference(s)