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Gcgtm1Rsy
Targeted Allele Detail
Summary
Symbol: Gcgtm1Rsy
Name: glucagon; targeted mutation 1, Randy J Seeley
MGI ID: MGI:6508044
Synonyms: Gcgflox
Gene: Gcg  Location: Chr2:62304874-62313994 bp, - strand  Genetic Position: Chr2, 35.85 cM
Alliance: Gcgtm1Rsy page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:281555
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  129
Mutation
description
Allele Type:    Targeted (Conditional ready)
Mutation:    Insertion
    Exon 2 is flanked by loxP sites. (J:281555)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Gcg Mutation:  35 strains or lines available
References
Original:  J:281555 Song Y, et al., Gut-Proglucagon-Derived Peptides Are Essential for Regulating Glucose Homeostasis in Mice. Cell Metab. 2019 Nov 5;30(5):976-986.e3
All:  6 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
01/20/2026
MGI 6.24
The Jackson Laboratory