Sema3g^{tm1.1(KOMP)Vlcg}
Targeted Allele Detail

Summary

• Symbol: Sema3g^{tm1.1(KOMP)Vlcg}
• Name: sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3G; targeted mutation 1.1, Velocigene
• MGI ID: MGI:6505528
• Synonyms: Sema3g^lacZ
• Gene: Sema3g Location: Chr14:30939830-30952309 bp, + strand Genetic Position: Chr14, 19.09 cM
• Alliance: Sema3g^{tm1.1(KOMP)Vlcg} page
• IMPC: Sema3g gene page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:241238
• Parent Cell Line: VGB6 (ES Cell)
• Strain of Origin: C57BL/6NTac
• Project Collection: KOMP-Regeneron

Mutation description

• Allele Type: Targeted (Null/knockout, Reporter)
• Mutations: Insertion, Intragenic deletion
• Mutation details: The insertion of Velocigene cassette ZEN-Ub1 created a deletion of size 10293bp between positions 32031100-32041392 of Chromosome 14 (Genome Build37). Cre-mediated recombination removed a floxed neomycin selection cassette. (J:241238)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Sema3g Mutation: 16 strains or lines available

References

• Original: J:241238 Liu X, et al., Semaphorin 3G Provides a Repulsive Guidance Cue to Lymphatic Endothelial Cells via Neuropilin-2/PlexinD1. Cell Rep. 2016 Nov 22;17(9):2299-2311
• All: 1 reference(s)