Sostdc1^em1Bcgen
Endonuclease-mediated Allele Detail

Summary

• Symbol: Sostdc1^em1Bcgen
• Name: sclerostin domain containing 1; endonuclease-mediated mutation 1, Biocytogen LLC
• MGI ID: MGI:6505471
• Synonyms: Sostdc1^EGFP
• Gene: Sostdc1 Location: Chr12:36364168-36368451 bp, + strand Genetic Position: Chr12, 16.82 cM, cytoband B2
• Alliance: Sostdc1^em1Bcgen page

Mutation origin

• Strain of Origin: C57BL/6

Mutation description

• Allele Type: Endonuclease-mediated (Reporter)
• Mutation: Insertion
• Mutation details: An EGFP-WPRE-polyA gene cassette was inserted immediately after the open reading frame of the gene by CRISPR/Cas9 genome editing technology. (J:295900)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Sostdc1 Mutation: 26 strains or lines available

References

• Original: J:295900 Wu X, et al., SOSTDC1-producing follicular helper T cells promote regulatory follicular T cell differentiation. Science. 2020 Aug 21;369(6506):984-988
• All: 2 reference(s)