Tg(CD207-HBEGF)#Dhka
Transgene Detail
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| Symbol: |
Tg(CD207-HBEGF)#Dhka |
| Name: |
transgene insertion, Daniel H Kaplan |
| MGI ID: |
MGI:6505458 |
| Synonyms: |
huDTR, HuLangerin-DTR |
| Transgene: |
Tg(CD207-HBEGF)#Dhka Location: unknown
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| Alliance: |
Tg(CD207-HBEGF)#Dhka page
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| Strain of Origin: |
C57BL/6 or FVB
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| Transgene Type: |
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Transgenic (Humanized sequence, Inserted expressed sequence) |
| Mutation: |
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Insertion
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Tg(CD207-HBEGF)#Dhka expresses
1 gene
Transgene expresses:
| Organism |
Expressed Gene |
Note |
| monkey |
HBEGF |
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Mutation details: The transgene consists of IRES sequences and the simian diphtheria toxin receptor (DTR) cDNA inserted into the 3' UTR of the human CD207 antigen or Langerin gene in BAC RP11-504O1.
(J:164731)
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| Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
| Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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| Original: |
J:164731 Bobr A, et al., Acute ablation of Langerhans cells enhances skin immune responses. J Immunol. 2010 Oct 15;185(8):4724-8 |
| All: |
5 reference(s) |
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Analysis Tools
