P2rx1^em1Zgz
Endonuclease-mediated Allele Detail

Summary

• Symbol: P2rx1^em1Zgz
• Name: purinergic receptor P2X, ligand-gated ion channel, 1; endonuclease-mediated mutation 1, Zhi-Gang Zhang
• MGI ID: MGI:6505300
• Gene: P2rx1 Location: Chr11:72889929-72906026 bp, + strand Genetic Position: Chr11, 45.09 cM
• Alliance: P2rx1^em1Zgz page

Mutation origin

• Strain of Origin: Not Specified

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• CRISPR/Cas9 technology deleted exons 2 and 3. (J:300996)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any P2rx1 Mutation: 29 strains or lines available

References

• Original: J:300996 Wang X, et al., Identification of a subset of immunosuppressive P2RX1-negative neutrophils in pancreatic cancer liver metastasis. Nat Commun. 2021 Jan 8;12(1):174
• All: 1 reference(s)