Mir26b^em1Jtm
Endonuclease-mediated Allele Detail

Summary

• Symbol: Mir26b^em1Jtm
• Name: microRNA 26b; endonuclease-mediated mutation 1, Joshua Mendell
• MGI ID: MGI:6501712
• Gene: Mir26b Location: Chr1:74433469-74433553 bp, + strand Genetic Position: Chr1, 38.54 cM
• Alliance: Mir26b^em1Jtm page

Mutation origin

• Strain of Origin: C57BL/6J

Mutation description

• Allele Type: Endonuclease-mediated (Not Specified)
• Mutation: Intragenic deletion
• Mutation details: CRISPR/cas9 genome editing is used to delete 31 base pairs. The deletion removes the 5' end including the seed sequence. (J:284175)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Mir26b Mutation: 2 strains or lines available

References

• Original: J:284175 Acharya A, et al., miR-26 suppresses adipocyte progenitor differentiation and fat production by targeting Fbxl19. Genes Dev. 2019 Oct 1;33(19-20):1367-1380
• All: 1 reference(s)