Mir26a-2^em1Jtm
Endonuclease-mediated Allele Detail

Summary

• Symbol: Mir26a-2^em1Jtm
• Name: microRNA 26a-2; endonuclease-mediated mutation 1, Joshua T Mendell
• MGI ID: MGI:6501710
• Gene: Mir26a-2 Location: Chr10:126831399-126831482 bp, + strand Genetic Position: Chr10, 74.45 cM
• Alliance: Mir26a-2^em1Jtm page

Mutation origin

• Strain of Origin: C57BL/6J

Mutation description

• Allele Type: Endonuclease-mediated (Not Specified)
• Mutation: Intragenic deletion
• Mutation details: CRISPR/cas9 genome editing is used to delete 20 bp removing the 5' end of the miRNA including the seed sequences. (J:284175)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Mir26a-2 Mutation: 2 strains or lines available

References

• Original: J:284175 Acharya A, et al., miR-26 suppresses adipocyte progenitor differentiation and fat production by targeting Fbxl19. Genes Dev. 2019 Oct 1;33(19-20):1367-1380
• All: 1 reference(s)