Scgb3a1^tm1.1Shk
Targeted Allele Detail

Summary

• Symbol: Scgb3a1^tm1.1Shk
• Name: secretoglobin, family 3A, member 1; targeted mutation 1.1, Shioko Kimura
• MGI ID: MGI:6500967
• Gene: Scgb3a1 Location: Chr11:49554437-49555945 bp, + strand Genetic Position: Chr11, 29.75 cM, cytoband B1.2
• Alliance: Scgb3a1^tm1.1Shk page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:276140
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: C57BL/6J x 129S4/SvJae

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: A targeting vector was designed to insert loxP site upstream of exon 2 and an FRT-flanked neomycin resistance (neo) cassette, followed by a second loxP site, was inserted downstream of exon 3 of the secretoglobin, family 3A, member 1 (Scgb3a1) gene. Cre recombinase removed the exons 2-3 and neo cassette. (J:378158)

Expression

In Mice Carrying this Mutation:

7 assay results

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Scgb3a1 Mutation: 9 strains or lines available

References

• Original: J:276140 Naizhen X, et al., Spatiotemporal Expression of Three Secretoglobin Proteins, SCGB1A1, SCGB3A1, and SCGB3A2, in Mouse Airway Epithelia. J Histochem Cytochem. 2019 Jun;67(6):453-463
• All: 2 reference(s)