Rasgrp4^tm1Wz
Targeted Allele Detail

Summary

• Symbol: Rasgrp4^tm1Wz
• Name: RAS guanyl releasing protein 4; targeted mutation 1, Weiguo Zhang
• MGI ID: MGI:6492166
• Gene: Rasgrp4 Location: Chr7:28834358-28853386 bp, + strand Genetic Position: Chr7, 16.94 cM, cytoband B1
• Alliance: Rasgrp4^tm1Wz page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:299313
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Exons 2, 3, and 4 of the gene were replaced by a PGK-neomycin selection cassette. (J:299313)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Rasgrp4 Mutation: 41 strains or lines available

References

• Original: J:299313 Zhu M, et al., The role of Ras guanine nucleotide releasing protein 4 in Fc epsilonRI-mediated signaling, mast cell function, and T cell development. J Biol Chem. 2012 Mar 9;287(11):8135-43
• All: 1 reference(s)