Tg(tetO-Cxcl12,-tdTomato)#Forsb
Transgene Detail

Summary

• Symbol: Tg(tetO-Cxcl12,-tdTomato)#Forsb
• Name: transgene insertion, E Forsberg
• MGI ID: MGI:6490253
• Synonyms: TgCXCL12
• Transgene: Tg(tetO-Cxcl12,-tdTomato)#Forsb Location: unknown
• Alliance: Tg(tetO-Cxcl12,-tdTomato)#Forsb page

Transgene origin

• Strain of Origin: C57BL/6

Transgene description

• Transgene Type: Transgenic (Epitope tag, Inducible, Inserted expressed sequence, Reporter)
• Inducer: doxycycline/tetracycline
• Mutation: Insertion
• Tg(tetO-Cxcl12,-tdTomato)#Forsb expresses 1 gene
  Transgene expresses:
  

  Organism	Expressed Gene	Note
  mouse	Cxcl2 (MGI:1340094)

• Mutation details: The transgenic construct contains a tetO (TRE) promoter directing expression of 6XHis tagged mouse Cxcl12 cDNA, a T2A cleavage site (mediates ribosomal skipping) and a tdTomato reporter. Founders were pooled. (J:292438)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:292438 Rajendiran S, et al., Ubiquitous overexpression of CXCL12 confers radiation protection and enhances mobilization of hematopoietic stem and progenitor cells. Stem Cells. 2020 May 22
• All: 1 reference(s)