Ace2^{tm2(ACE2)Agel}
Targeted Allele Detail

Summary

• Symbol: Ace2^{tm2(ACE2)Agel}
• Name: angiotensin converting enzyme 2; targeted mutation 2, Animal Gene Editing Laboratory
• MGI ID: MGI:6478987
• Gene: Ace2 Location: ChrX:162922338-162971414 bp, + strand Genetic Position: ChrX, 76.12 cM, cytoband F5
• Alliance: Ace2^{tm2(ACE2)Agel} page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:297160
• Parent Cell Line: RW-4 (ES Cell)
• Strain of Origin: 129X1/SvJ

Mutation description

• Allele Type: Targeted (Conditional ready, Inserted expressed sequence)
• Mutation: Insertion
• The human sequence was knocked into the endogenous gene to provide for conditional expression. (J:297160)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Ace2 Mutation: 54 strains or lines available

References

• Original: J:297160 Yu WP, Unpublished Alleles from the Animal Gene Editing Laboratory. MGI Direct Data Submission. 2020
• All: 1 reference(s)