Spag17^pcdo
Chemically induced Allele Detail

Summary

• Symbol: Spag17^pcdo
• Name: sperm associated antigen 17; primary ciliary dyskinesia only
• MGI ID: MGI:6478923
• Synonyms: Spag17^c.5236A>T
• Gene: Spag17 Location: Chr3:99792722-100050638 bp, + strand Genetic Position: Chr3, 43.25 cM, cytoband F3
• Alliance: Spag17^pcdo page

Mutation origin

• Strain of Origin: Not Applicable

Mutation description

• Allele Type: Chemically induced (ENU) (Hypomorph)
• Mutation: Single point mutation
• Mutation details: This ENU-induced mutation is a c.5236A>T substitution that creates a nonsense mutation at lysine codon 1746 (p.K1746*). (J:297491)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Spag17 Mutation: 107 strains or lines available

References

• Original: J:297491 Abdelhamed Z, et al., A novel hypomorphic allele of Spag17 causes primary ciliary dyskinesia phenotypes in mice. Dis Model Mech. 2020 Oct 30;13(10):dmm045344
• All: 1 reference(s)