Gt(ROSA)26Sor^{tm15(Jun)Rsky}
Targeted Allele Detail

Summary

• Symbol: Gt(ROSA)26Sor^{tm15(Jun)Rsky}
• Name: gene trap ROSA 26, Philippe Soriano; targeted mutation 15, Klaus Rajewsky
• MGI ID: MGI:6478892
• Synonyms: R26c-Junstopf^f
• Gene: Gt(ROSA)26Sor Location: Chr6:113044389-113054205 bp, - strand Genetic Position: Chr6, 52.73 cM
• Alliance: Gt(ROSA)26Sor^{tm15(Jun)Rsky} page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:254442
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Conditional ready, Inserted expressed sequence, Reporter)
• Mutation: Insertion
• Mutation details: The targeting construct inserted into the locus a polyadenylation sequence, CAG promoter, floxed STOP cassette, c-Jun, 271 bp spacer, IRES, EGFP reporter gene, 271 bp spacer, and polyadenylation sequence. (J:254442)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Gt(ROSA)26Sor Mutation: 1089 strains or lines available

References

• Original: J:254442 Fazal SV, et al., Graded Elevation of c-Jun in Schwann Cells In Vivo: Gene Dosage Determines Effects on Development, Remyelination, Tumorigenesis, and Hypomyelination. J Neurosci. 2017 Dec 13;37(50):12297-12313
• All: 4 reference(s)