Il6st^tm5Thir
Targeted Allele Detail

Summary

• Symbol: Il6st^tm5Thir
• Name: interleukin 6 signal transducer; targeted mutation 5, Toshio Hirano
• MGI ID: MGI:6477621
• Synonyms: gp130^WH
• Gene: Il6st Location: Chr13:112600604-112643394 bp, + strand Genetic Position: Chr13, 63.73 cM
• Alliance: Il6st^tm5Thir page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:104881
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Humanized sequence)
• Mutations: Insertion, Nucleotide substitutions
• Mutation details: cDNA encoding the transmembrane and cytoplasmic domains of human IL6ST replaced the corresponding sequence of the mouse locus, yielding a mouse-human chimeric protein. (J:104881)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Il6st Mutation: 84 strains or lines available

References

• Original: J:104881 The RIKEN BioResource Center, Information obtained from The RIKEN BioResource Center. Unpublished. 2006-2013
• All: 1 reference(s)