Tmbim1^em1Cya
Endonuclease-mediated Allele Detail

Summary

• Symbol: Tmbim1^em1Cya
• Name: transmembrane BAX inhibitor motif containing 1; endonuclease-mediated mutation 1, Cyagen Biosciences
• MGI ID: MGI:6477608
• Synonyms: Tmbim1^em1Cgen, Tmbim1^em1cyagen
• Gene: Tmbim1 Location: Chr1:74327406-74343495 bp, - strand Genetic Position: Chr1, 38.53 cM
• Alliance: Tmbim1^em1Cya page

Mutation origin

• Strain of Origin: C57BL/6J

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• Exon 2~12 were selected as target site. (J:273425)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Tmbim1 Mutation: 29 strains or lines available

References

• Original: J:273425 Gong F, et al., Up regulated Tmbim1 activation promotes high fat diet (HFD)-induced cardiomyopathy by enhancement of inflammation and oxidative stress. Biochem Biophys Res Commun. 2018 Oct 12;504(4):797-804
• All: 1 reference(s)