Cntn2^{tm1.1(cre/EGFP)Nmun}
Targeted Allele Detail

Summary

• Symbol: Cntn2^{tm1.1(cre/EGFP)Nmun}
• Name: contactin 2; targeted mutation 1.1, Nikhil V Munshi
• MGI ID: MGI:6476947
• Synonyms: Cntn2^{3'UTR-IRES-Cre-EGFP}, Cntn2^{tm1.1(cre/EGFP)Cgen}, Cntn2^{tm1.1(cre/EGFP)Cya}.
• Gene: Cntn2 Location: Chr1:132437163-132470989 bp, - strand Genetic Position: Chr1, 57.42 cM
• Alliance: Cntn2^{tm1.1(cre/EGFP)Nmun} page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:247134
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Recombinase, Reporter)
• Mutation: Insertion
• Cntn2^{tm1.1(cre/EGFP)Nmun} expression driven by 1 gene
  Knock-in expression driven by:
  

  Organism	Driver Gene	Note
  mouse	Cntn2 (MGI:104518)

• Mutation details: The targeting vector inserted downstream of the stop codon an IRES, cre recombinase gene fused with the EGFP reporter gene, and FRT-flanked neomycin resistance cassette. Flp-mediated recombination removed the selection cassette. (J:247134)

Recombinase activity

Activity:	Tissue activity of this recombinase allele
Driver:	Cntn2 (mouse) Summary of all recombinase alleles driven by Cntn2. Comparative matrix view of recombinase activities Alliance mouse Cntn2 gene page

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Cntn2 Mutation: 53 strains or lines available

References

• Original: J:247134 Bhattacharyya S, et al., Phenotypically silent Cre recombination within the postnatal ventricular conduction system. PLoS One. 2017;12(3):e0174517
• All: 2 reference(s)