Gt(ROSA)26Sor^{tm5.2(CAG-GCaMP3)Imayo}
Targeted Allele Detail

Summary

• Symbol: Gt(ROSA)26Sor^{tm5.2(CAG-GCaMP3)Imayo}
• Name: gene trap ROSA 26, Philippe Soriano; targeted mutation 5.2, Itaru Imayoshi
• MGI ID: MGI:6474230
• Synonyms: R26-CAG-FRT-GCaMP3
• Gene: Gt(ROSA)26Sor Location: Chr6:113044389-113054205 bp, - strand Genetic Position: Chr6, 52.73 cM
• Alliance: Gt(ROSA)26Sor^{tm5.2(CAG-GCaMP3)Imayo} page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:297198
• Parent Cell Line: TC1/TC-1 (ES Cell)
• Strain of Origin: 129S6/SvEvTac

Mutation description

• Allele Type: Targeted (Reporter)
• Mutation: Insertion
• Mutation details: The transgene construct is knocked into into 3UTR region a splice acceptor flanked puro cassette, CAG promoter, floxed stop cassette, FRT-flanked stop cassette, GCaMP3, and WPRE sequence. Flp-mediated recombination removed the FRT-flanked stop cassette. Cre-mediated recombination removed the floxed stop cassette. (J:297198)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Gt(ROSA)26Sor Mutation: 1089 strains or lines available

References

• Original: J:297198 Ebina T, et al., 3D clustering of GABAergic neurons enhances inhibitory actions on excitatory neurons in the mouse visual cortex. Cell Rep. 2014 Dec 11;9(5):1896-1907
• All: 1 reference(s)