Cacna1a^{tm3.1(CACNA1A)Ttan}
Targeted Allele Detail

Summary

• Symbol: Cacna1a^{tm3.1(CACNA1A)Ttan}
• Name: calcium channel, voltage-dependent, P/Q type, alpha 1A subunit; targeted mutation 3.1, Tsutomu Tanabe
• MGI ID: MGI:6474215
• Synonyms: Cacna1a KI#3.1
• Gene: Cacna1a Location: Chr8:85065268-85366875 bp, + strand Genetic Position: Chr8, 40.95 cM
• Alliance: Cacna1a^{tm3.1(CACNA1A)Ttan} page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:104881
• Parent Cell Line: J1 (ES Cell)
• Strain of Origin: 129S4/SvJae

Mutation description

• Allele Type: Targeted (Humanized sequence)
• Mutation: Insertion
• Mutation details: The human CACNA1 cDNA with 28 CAG repeat and FLAG-tag were inserted into mouse Cacna1a exon 1. Flp-meditated recombination removed the hygromycin cassette. (J:104881, J:123243)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Cacna1a Mutation: 115 strains or lines available

References

• Original: J:104881 The RIKEN BioResource Center, Information obtained from The RIKEN BioResource Center. Unpublished. 2006-2013
• All: 2 reference(s)