Gt(ROSA)26Sortm1(CAG-SNCA)Tanj
Targeted Allele Detail
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Symbol: |
Gt(ROSA)26Sortm1(CAG-SNCA)Tanj |
Name: |
gene trap ROSA 26, Philippe Soriano; targeted mutation 1, Kunikazu Tanji |
MGI ID: |
MGI:6473659 |
Synonyms: |
Syn-flox |
Gene: |
Gt(ROSA)26Sor Location: Chr6:113044389-113054205 bp, - strand Genetic Position: Chr6, 52.73 cM
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Alliance: |
Gt(ROSA)26Sortm1(CAG-SNCA)Tanj page
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Allele Type: |
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Targeted (Conditional ready, Humanized sequence, Inserted expressed sequence) |
Mutation: |
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Insertion
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Gt(ROSA)26Sortm1(CAG-SNCA)Tanj expresses
1 gene
Knock-in expresses:
Organism |
Expressed Gene |
Homolog in Mouse |
Note |
human |
SNCA (6622) |
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Mutation details: The targeting construct inserted into the locus a CAG promoter, a loxP-flanked STOP cassette with 3 SV40 polyadenylation sequences and the human alpha-synuclein cDNA, woodchuck hepatitis virus posttrascriptional regulatory element (WPRE), and bGH polyl(A). Expression of the gene can only be achieved by cre-mediated removal of the floxed neo STOP cassette.
(J:283567)
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View phenotypes and curated references for all genotypes (concatenated display).
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Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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Carrying any Gt(ROSA)26Sor Mutation: |
942 strains or lines available
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Original: |
J:283567 Tanji K, et al., A mouse model of adult-onset multiple system atrophy. Neurobiol Dis. 2019 Jul;127:339-349 |
All: |
1 reference(s) |
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